Notably, there has been widespread interest in the multiple possible uses of nanobubbles (NB) with a diameter of less than 100 nm. The introduction of NB technology in Japan, the United States, Europe, and other countries shows that it has enormous potential, even in the early stages of exploration in various industries. However, the full extent of its impact on aquaculture is not yet fully understood. Nanobubbles have shown promising results in improving water quality in aquaculture systems, increasing oxygen levels, and promoting fish health. However, further research and experiments are needed to determine the optimal conditions for their application and to fully understand their long-term effects on fish growth and overall production efficiency. Not only fish productivity highly positively correlated with dissolved oxygen (DO) concentration in the aquatic environment but also the size of the bubbles is inversely related to the solubility and stability of DO. Therefore, it plays a crucial role in this interdependence. However, it is worth noting that existing aquaculture practices often unknown the importance of oxygen nanobubbles. These nanobubbles can be quickly generated and distributed on the water surface using various devices, creating millions of oxygens nanobubbles in a limited volume of water to have a significant impact on the regulation of aquatic environments. Using nanobubbles in aeration technology is a promising option for the blue revolution in aquaculture practices. The article offers a comprehensive overview, providing valuable insights into the significance and potential benefits of NB technology in the aquaculture sector.